COMPUTATIONAL CANCER BIOLOGY LABORATORY
The Azizi Lab develops machine learning, artificial intelligence (AI), and statistical frameworks to uncover how tumors evolve, resist therapies, and evade the immune system. Our interdisciplinary team integrates single-cell and spatial genomic, and imaging data to reconstruct the dynamic interactions between cancer, immune, and stromal cells directly from patient specimens.
Our research spans the development of generative and causal frameworks and foundation models for tumor–immune dynamics, and AI-guided hypothesis generation and experimental validation. Our vision is to bridge data-driven discovery and mechanistic understanding, advancing precision oncology through interpretable, biologically grounded machine learning and AI.
Our lab is primarily affiliated with the Biomedical Engineering Department and the Irving Institute for Cancer Dynamics (IICD) at Columbia University. We are also affiliated with the Computer Science Department, Data Science Institute and the Herbert Irving Comprehensive Cancer Center. Our work is supported by funding from the NIH National Human Genome Research Institute, the NIH National Cancer Institute, the NSF, and the Chan Zuckerberg Initiative.
The Azizi Lab develops machine learning, artificial intelligence (AI), and statistical frameworks to uncover how tumors evolve, resist therapies, and evade the immune system. Our interdisciplinary team integrates single-cell and spatial genomic, and imaging data to reconstruct the dynamic interactions between cancer, immune, and stromal cells directly from patient specimens.
Our research spans the development of generative and causal frameworks and foundation models for tumor–immune dynamics, and AI-guided hypothesis generation and experimental validation. Our vision is to bridge data-driven discovery and mechanistic understanding, advancing precision oncology through interpretable, biologically grounded machine learning and AI.
Our lab is primarily affiliated with the Biomedical Engineering Department and the Irving Institute for Cancer Dynamics (IICD) at Columbia University. We are also affiliated with the Computer Science Department, Data Science Institute and the Herbert Irving Comprehensive Cancer Center. Our work is supported by funding from the NIH National Human Genome Research Institute, the NIH National Cancer Institute, the NSF, and the Chan Zuckerberg Initiative.
